What is P-450 CYP2D6, Cytochrome?
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A polymorphic enzyme that catalyzes the hydroxylation of debrisoquine. It also metabolizes several antidepressants and neuroleptics. This enzyme is deficient in up to 10 percent of the population. (Psychopharmacol Bull 1995; 31(2): 327-331) EC 1.14.99.-.