What is U-50,488H?
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A non-peptide, kappa-opioid receptor agonist which has also been found to stimulate the release of adrenocorticotropin (CORTICOTROPIN) via the release of hypothalmic arginine vasopressin (ARGIPRESSIN) and CORTICOTROPIN-RELEASING HORMONE. (From J Pharmacol Exp Ther 1997;280(1):416-21)